Use UniProt Q8WTV0 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL1914272 Target Snapshot
Scavenger receptor class B member 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q8WTV0. Use UniProt Q8WTV0 as the stable identity anchor, then attach disease evidence before program review.
Scavenger receptor class B member 1
Review this target as Scavenger receptor class B member 1, mapped to UniProt Q8WTV0. Sequence length is 552 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Scavenger receptor class B member 1 as ChEMBL target CHEMBL1914272, mapped to UniProt Q8WTV0. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Scavenger receptor class B member 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q8WTV0 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Scavenger receptor class B member 1 |
| UniProt Accession | Q8WTV0 |
| Component Type | Protein |
| Sequence Length | 552 aa |
Scavenger receptor class B member 1
How to read this target
Review this target as Scavenger receptor class B member 1, mapped to UniProt Q8WTV0. Sequence length is 552 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1914885 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL2179485 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL2179493 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL2179499 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL2179500 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL2179501 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL2179502 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL2179504 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL2179507 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL2179508 | 8.82 | IC50 | 1.5 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 4 assays, 53 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 53 | 7.6 |