G protein-activated inward rectifier potassium channel 4 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P48544. Use UniProt P48544 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P48544 as the stable identity anchor, then attach disease evidence before program review.
G protein-activated inward rectifier potassium channel 4
Review this target as G protein-activated inward rectifier potassium channel 4, mapped to UniProt P48544. Sequence length is 419 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats G protein-activated inward rectifier potassium channel 4 as ChEMBL target CHEMBL1914278, mapped to UniProt P48544. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | G protein-activated inward rectifier potassium channel 4 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P48544 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | G protein-activated inward rectifier potassium channel 4 |
| UniProt Accession | P48544 |
| Component Type | Protein |
| Sequence Length | 419 aa |
G protein-activated inward rectifier potassium channel 4
Review this target as G protein-activated inward rectifier potassium channel 4, mapped to UniProt P48544. Sequence length is 419 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5751984 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5804730 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5982340 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL6045550 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5757725 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL5841402 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL6025760 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL6058410 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL5756136 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL5921371 | 8.3 | IC50 | 5.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 29 | 7.8 |