Tubulin beta-1 chain · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9H4B7. Use UniProt Q9H4B7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9H4B7 as the stable identity anchor, then attach disease evidence before program review.
Tubulin beta-1 chain
Review this target as Tubulin beta-1 chain, mapped to UniProt Q9H4B7. Sequence length is 451 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Tubulin beta-1 chain as ChEMBL target CHEMBL1915, mapped to UniProt Q9H4B7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Tubulin beta-1 chain |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9H4B7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tubulin beta-1 chain |
| UniProt Accession | Q9H4B7 |
| Component Type | Protein |
| Sequence Length | 451 aa |
Tubulin beta-1 chain
Review this target as Tubulin beta-1 chain, mapped to UniProt Q9H4B7. Sequence length is 451 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL370250 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL193716 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL195572 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL67 | 6.75 | IC50 | 180.0 | Preclinical |
| CHEMBL47426 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL182319 | 6.58 | Kd | 260.0 | Clinical |
| CHEMBL195840 | 6.35 | IC50 | 450.0 | Preclinical |
| CHEMBL9859 | 6.34 | IC50 | 460.0 | Preclinical |
| CHEMBL371839 | 6.33 | IC50 | 470.0 | Preclinical |
| CHEMBL192739 | 6.3 | IC50 | 500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 7 | 67 | 5.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 0 | — |