Natural resistance-associated macrophage protein 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P49281. Use UniProt P49281 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P49281 as the stable identity anchor, then attach disease evidence before program review.
Natural resistance-associated macrophage protein 2
Review this target as Natural resistance-associated macrophage protein 2, mapped to UniProt P49281. Sequence length is 568 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Natural resistance-associated macrophage protein 2 as ChEMBL target CHEMBL1932895, mapped to UniProt P49281. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Natural resistance-associated macrophage protein 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P49281 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Natural resistance-associated macrophage protein 2 |
| UniProt Accession | P49281 |
| Component Type | Protein |
| Sequence Length | 568 aa |
Natural resistance-associated macrophage protein 2
Review this target as Natural resistance-associated macrophage protein 2, mapped to UniProt P49281. Sequence length is 568 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3145266 | 7.22 | IC50 | 60.0 | Preclinical |
| CHEMBL2079088 | 6.85 | IC50 | 140.0 | Preclinical |
| CHEMBL1933782 | 6.82 | IC50 | 150.0 | Preclinical |
| CHEMBL3145267 | 6.82 | IC50 | 150.0 | Preclinical |
| CHEMBL3145276 | 6.77 | IC50 | 170.0 | Preclinical |
| CHEMBL3145277 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL1933791 | 6.68 | IC50 | 210.0 | Preclinical |
| CHEMBL1933792 | 6.58 | IC50 | 260.0 | Preclinical |
| CHEMBL3145278 | 6.58 | IC50 | 260.0 | Preclinical |
| CHEMBL1933793 | 6.57 | IC50 | 270.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 9 | 43 | 6.2 |
| single protein format | 1 | 0 | — |