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Target Snapshot

CHEMBL1932905 Target Snapshot

17-beta-hydroxysteroid dehydrogenase type 3 · SINGLE PROTEIN · Mus musculus

1Compounds
1Assays
0Approved Drugs
1.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P70385. Use UniProt P70385 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P70385 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats 17-beta-hydroxysteroid dehydrogenase type 3 as ChEMBL target CHEMBL1932905, mapped to UniProt P70385. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
17-beta-hydroxysteroid dehydrogenase type 3
SINGLE PROTEIN · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL1932905
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P70385
17-beta-hydroxysteroid dehydrogenase type 3
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether 17-beta-hydroxysteroid dehydrogenase type 3 is the right protein anchor across sources, using UniProt P70385 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein Label17-beta-hydroxysteroid dehydrogenase type 3
UniProt AccessionP70385
Component TypeProtein
Sequence Length305 aa

17-beta-hydroxysteroid dehydrogenase type 3

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as 17-beta-hydroxysteroid dehydrogenase type 3, mapped to UniProt P70385. Sequence length is 305 aa.

Mapped IDP70385
Review name17-beta-hydroxysteroid dehydrogenase type 3
OrganismMus musculus
Assay Mix

Activity Type Distribution

IC501.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1934493 7.4 IC50 40.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
1
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

1
Total Assays
1
Tested Compounds
1
Assay Types
Binding — 1 assays, 1 compounds
BAO Format Assays Compounds Avg pChEMBL
tissue-based format 1 1 7.4

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine