ATP-binding cassette sub-family C member 8 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q09429. Use UniProt Q09429 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q09429 as the stable identity anchor, then attach disease evidence before program review.
ATP-binding cassette sub-family C member 8
Review this target as ATP-binding cassette sub-family C member 8, mapped to UniProt Q09429. Sequence length is 1582 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats ATP-binding cassette sub-family C member 8 as ChEMBL target CHEMBL1944490, mapped to UniProt Q09429. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether ATP-binding cassette sub-family C member 8 is the right protein anchor across sources, using UniProt Q09429 as the stable mapping.
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| Preferred Name | ATP-binding cassette sub-family C member 8 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q09429 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | ATP-binding cassette sub-family C member 8 |
| UniProt Accession | Q09429 |
| Component Type | Protein |
| Sequence Length | 1582 aa |
ATP-binding cassette sub-family C member 8
Review this target as ATP-binding cassette sub-family C member 8, mapped to UniProt Q09429. Sequence length is 1582 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1946412 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL191539 | 6.62 | IC50 | 240.0 | Preclinical |
| CHEMBL363989 | 6.55 | IC50 | 280.0 | Preclinical |
| CHEMBL1946140 | 6.46 | IC50 | 350.0 | Preclinical |
| CHEMBL112668 | 6.32 | IC50 | 480.0 | Preclinical |
| CHEMBL1946272 | 6.28 | IC50 | 520.0 | Preclinical |
| CHEMBL1945810 | 6.21 | IC50 | 620.0 | Preclinical |
| CHEMBL115565 | 6.12 | IC50 | 760.0 | Preclinical |
| CHEMBL1946139 | 5.85 | IC50 | 1410.0 | Preclinical |
| CHEMBL1946410 | 5.78 | IC50 | 1670.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 5 | 24 | 5.7 |
| single protein format | 5 | 0 | — |