Glycylpeptide N-tetradecanoyltransferase · SINGLE PROTEIN · Leishmania major
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As of 2026-09-14Protein identity stays anchored to UniProt Q4Q5S8. Use UniProt Q4Q5S8 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q4Q5S8 as the stable identity anchor, then attach disease evidence before program review.
Glycylpeptide N-tetradecanoyltransferase
Review this target as Glycylpeptide N-tetradecanoyltransferase, mapped to UniProt Q4Q5S8. Sequence length is 421 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Glycylpeptide N-tetradecanoyltransferase as ChEMBL target CHEMBL1949483, mapped to UniProt Q4Q5S8. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Glycylpeptide N-tetradecanoyltransferase |
| Target Type | SINGLE PROTEIN |
| Organism | Leishmania major |
| UniProt | Q4Q5S8 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glycylpeptide N-tetradecanoyltransferase |
| UniProt Accession | Q4Q5S8 |
| Component Type | Protein |
| Sequence Length | 421 aa |
Glycylpeptide N-tetradecanoyltransferase
Review this target as Glycylpeptide N-tetradecanoyltransferase, mapped to UniProt Q4Q5S8. Sequence length is 421 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3358114 | 9.47 | Ki | 0.34 | Preclinical |
| CHEMBL3357693 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL3358114 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL3358119 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL3358120 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL3358121 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4532268 | 8.89 | Ki | 1.3 | Preclinical |
| CHEMBL3357688 | 8.85 | Ki | 1.4 | Preclinical |
| CHEMBL3912318 | 8.8 | Ki | 1.6 | Preclinical |
| CHEMBL1230468 | 8.7 | IC50 | 2.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 6 | 11 | 7.7 |
| single protein format | 4 | 61 | 7.5 |