COUP transcription factor 2 · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P24468. Use UniProt P24468 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P24468 as the stable identity anchor, then attach disease evidence before program review.
COUP transcription factor 2
Review this target as COUP transcription factor 2, mapped to UniProt P24468. Sequence length is 414 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats COUP transcription factor 2 as ChEMBL target CHEMBL1961790, mapped to UniProt P24468. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether COUP transcription factor 2 is the right protein anchor across sources, using UniProt P24468 as the stable mapping.
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| Preferred Name | COUP transcription factor 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P24468 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | COUP transcription factor 2 |
| UniProt Accession | P24468 |
| Component Type | Protein |
| Sequence Length | 414 aa |
COUP transcription factor 2
Review this target as COUP transcription factor 2, mapped to UniProt P24468. Sequence length is 414 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1699691 | 8.12 | IC50 | 7.64 | Preclinical |
| CHEMBL1702665 | 7.65 | IC50 | 22.34 | Preclinical |
| CHEMBL225963 | 7.21 | IC50 | 61.93 | Preclinical |
| CHEMBL1567944 | 6.68 | IC50 | 208.53 | Preclinical |
| CHEMBL509617 | 6.44 | IC50 | 359.98 | Preclinical |
| CHEMBL1721226 | 6.29 | IC50 | 518.61 | Preclinical |
| CHEMBL1423004 | 6.25 | IC50 | 567.98 | Preclinical |
| CHEMBL1323872 | 6.21 | IC50 | 616.83 | Preclinical |
| CHEMBL1415184 | 6.2 | IC50 | 628.26 | Preclinical |
| CHEMBL1523841 | 6.13 | IC50 | 737.11 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 219 | 5.2 |