Epoxide hydrolase 1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P07099. Use UniProt P07099 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P07099 as the stable identity anchor, then attach disease evidence before program review.
Epoxide hydrolase 1
Review this target as Epoxide hydrolase 1, mapped to UniProt P07099. Sequence length is 455 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Epoxide hydrolase 1 as ChEMBL target CHEMBL1968, mapped to UniProt P07099. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Epoxide hydrolase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P07099 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Epoxide hydrolase 1 |
| UniProt Accession | P07099 |
| Component Type | Protein |
| Sequence Length | 455 aa |
Epoxide hydrolase 1
Review this target as Epoxide hydrolase 1, mapped to UniProt P07099. Sequence length is 455 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1257517 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL1257759 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL3642246 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL1257880 | 9.1 | IC50 | 0.8 | Preclinical |
| CHEMBL3642245 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL4741234 | 9.03 | IC50 | 0.94 | Preclinical |
| CHEMBL215121 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL215908 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL215999 | 8.96 | IC50 | 1.1 | Preclinical |
| CHEMBL217758 | 8.96 | IC50 | 1.1 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 7 | 158 | 6.7 |
| assay format | 6 | 48 | 5.4 |
| tissue-based format | 3 | 0 | — |
| cell-based format | 1 | 0 | — |
| organism-based format | 1 | 145 | 6.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| microsome format | 8 | 0 | — |
| cell-based format | 2 | 0 | — |