T-cell surface glycoprotein CD3 epsilon chain · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13T-cell surface glycoprotein CD3 epsilon chain shows approved-linked disease relevance led by type 1 diabetes mellitus. 5 more disease programs remain visible in the same review block. 3 linked drugs keep the current disease frame grounded. Protein identity stays anchored to UniProt P07766. Start with type 1 diabetes mellitus, then reuse UniProt P07766 as the stable protein anchor across project notes and exports.
Start with type 1 diabetes mellitus, then reuse UniProt P07766 as the stable protein anchor across project notes and exports.
T-cell surface glycoprotein CD3 epsilon chain shows approved-linked disease relevance led by type 1 diabetes mellitus. 5 more disease programs remain visible in the same review block. 3 linked drugs remain visible in the same block.
Start review with type 1 diabetes mellitus because it currently carries approved-linked support. Linked drugs include HOKT3, OTELIXIZUMAB, TEPLIZUMAB. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyT-cell surface glycoprotein CD3 epsilon chain
Review this target as T-cell surface glycoprotein CD3 epsilon chain, mapped to UniProt P07766. Sequence length is 207 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats T-cell surface glycoprotein CD3 epsilon chain as ChEMBL target CHEMBL1975, mapped to UniProt P07766. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
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Start here when your first question is whether T-cell surface glycoprotein CD3 epsilon chain is the right protein anchor across sources, using UniProt P07766 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why type 1 diabetes mellitus is currently framed as approved-linked support. It currently carries 3 linked drugs in the same disease frame.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | T-cell surface glycoprotein CD3 epsilon chain |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P07766 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | T-cell surface glycoprotein CD3 epsilon chain |
| UniProt Accession | P07766 |
| Component Type | Protein |
| Sequence Length | 207 aa |
T-cell surface glycoprotein CD3 epsilon chain
Review this target as T-cell surface glycoprotein CD3 epsilon chain, mapped to UniProt P07766. Sequence length is 207 aa.
Open Targets-ready disease context using the current target-indication evidence contract.
T-cell surface glycoprotein CD3 epsilon chain shows approved-linked disease relevance led by type 1 diabetes mellitus. 5 more disease programs remain visible in the same review block.
Start review with type 1 diabetes mellitus because it currently carries approved-linked support. Linked drugs include HOKT3, OTELIXIZUMAB, TEPLIZUMAB. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.