Retinoic acid receptor RXR-gamma · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P48443. Use UniProt P48443 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P48443 as the stable identity anchor, then attach disease evidence before program review.
Retinoic acid receptor RXR-gamma
Review this target as Retinoic acid receptor RXR-gamma, mapped to UniProt P48443. Sequence length is 463 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Retinoic acid receptor RXR-gamma as ChEMBL target CHEMBL2004, mapped to UniProt P48443. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Retinoic acid receptor RXR-gamma |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P48443 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Retinoic acid receptor RXR-gamma |
| UniProt Accession | P48443 |
| Component Type | Protein |
| Sequence Length | 463 aa |
Retinoic acid receptor RXR-gamma
Review this target as Retinoic acid receptor RXR-gamma, mapped to UniProt P48443. Sequence length is 463 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL75133 | 10.1 | EC50 | 0.08 | Clinical |
| CHEMBL5404648 | 9.22 | EC50 | 0.6 | Preclinical |
| CHEMBL69091 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL38 | 8.85 | Ki | 1.4 | Approved |
| CHEMBL69091 | 8.74 | Kd | 1.8 | Preclinical |
| CHEMBL38 | 8.7 | EC50 | 2.0 | Approved |
| CHEMBL96184 | 8.7 | EC50 | 2.0 | Preclinical |
| CHEMBL337393 | 8.55 | Ki | 2.8 | Preclinical |
| CHEMBL130232 | 8.54 | Ki | 2.9 | Preclinical |
| CHEMBL5289973 | 8.52 | EC50 | 3.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 67 | 133 | 5.8 |
| single protein format | 46 | 103 | 7.1 |
| assay format | 10 | 41 | 5.7 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 15 | 48 | 7.0 |
| assay format | 5 | 11 | 6.8 |