Type I iodothyronine deiodinase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Type I iodothyronine deiodinase shows approved-linked disease relevance led by Abnormality of the thyroid gland. 5 more disease programs remain visible in the same review block. 1 linked drug keeps the current disease frame grounded. Protein identity stays anchored to UniProt P49895. Start with Abnormality of the thyroid gland, then reuse UniProt P49895 as the stable protein anchor across project notes and exports.
Start with Abnormality of the thyroid gland, then reuse UniProt P49895 as the stable protein anchor across project notes and exports.
Type I iodothyronine deiodinase shows approved-linked disease relevance led by Abnormality of the thyroid gland. 5 more disease programs remain visible in the same review block. 1 linked drug remains visible in the same block.
Start review with Abnormality of the thyroid gland because it currently carries approved-linked support. Linked drugs include PROPYLTHIOURACIL. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyType I iodothyronine deiodinase
Review this target as Type I iodothyronine deiodinase, mapped to UniProt P49895. Sequence length is 249 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Type I iodothyronine deiodinase as ChEMBL target CHEMBL2019, mapped to UniProt P49895. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
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Start here when your first question is whether Type I iodothyronine deiodinase is the right protein anchor across sources, using UniProt P49895 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why Abnormality of the thyroid gland is currently framed as approved-linked support. It currently carries 1 linked drug in the same disease frame.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
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| Preferred Name | Type I iodothyronine deiodinase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P49895 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Type I iodothyronine deiodinase |
| UniProt Accession | P49895 |
| Component Type | Protein |
| Sequence Length | 249 aa |
Type I iodothyronine deiodinase
Review this target as Type I iodothyronine deiodinase, mapped to UniProt P49895. Sequence length is 249 aa.
Open Targets-ready disease context using the current target-indication evidence contract.
Type I iodothyronine deiodinase shows approved-linked disease relevance led by Abnormality of the thyroid gland. 5 more disease programs remain visible in the same review block.
Start review with Abnormality of the thyroid gland because it currently carries approved-linked support. Linked drugs include PROPYLTHIOURACIL. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.