Receptor-type tyrosine-protein kinase FLT3 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q00342. Use UniProt Q00342 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q00342 as the stable identity anchor, then attach disease evidence before program review.
Receptor-type tyrosine-protein kinase FLT3
Review this target as Receptor-type tyrosine-protein kinase FLT3, mapped to UniProt Q00342. Sequence length is 1000 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Receptor-type tyrosine-protein kinase FLT3 as ChEMBL target CHEMBL2034796, mapped to UniProt Q00342. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Receptor-type tyrosine-protein kinase FLT3 is the right protein anchor across sources, using UniProt Q00342 as the stable mapping.
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| Preferred Name | Receptor-type tyrosine-protein kinase FLT3 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q00342 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Receptor-type tyrosine-protein kinase FLT3 |
| UniProt Accession | Q00342 |
| Component Type | Protein |
| Sequence Length | 1000 aa |
Receptor-type tyrosine-protein kinase FLT3
Review this target as Receptor-type tyrosine-protein kinase FLT3, mapped to UniProt Q00342. Sequence length is 1000 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL603469 | 8.82 | IC50 | 1.5 | Clinical |
| CHEMBL5564780 | 8.11 | IC50 | 7.85 | Preclinical |
| CHEMBL2037224 | 5.68 | IC50 | 2100.0 | Preclinical |
| CHEMBL2037209 | 5.33 | IC50 | 4700.0 | Preclinical |
| CHEMBL2037226 | 5.29 | IC50 | 5100.0 | Preclinical |
| CHEMBL2037220 | 5.26 | IC50 | 5500.0 | Preclinical |
| CHEMBL2037211 | 5.19 | IC50 | 6400.0 | Preclinical |
| CHEMBL2037208 | 5.03 | IC50 | 9400.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 12 | 8 | 6.3 |
| assay format | 8 | 0 | — |
| single protein format | 2 | 0 | — |