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Target Snapshot

CHEMBL2034798 Target Snapshot

Mast/stem cell growth factor receptor Kit · SINGLE PROTEIN · Mus musculus

47Compounds
4Assays
0Approved Drugs
8.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P05532. Use UniProt P05532 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P05532 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Mast/stem cell growth factor receptor Kit as ChEMBL target CHEMBL2034798, mapped to UniProt P05532. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Mast/stem cell growth factor receptor Kit
SINGLE PROTEIN · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL2034798
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P05532
Mast/stem cell growth factor receptor Kit
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Mast/stem cell growth factor receptor Kit is the right protein anchor across sources, using UniProt P05532 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelMast/stem cell growth factor receptor Kit
UniProt AccessionP05532
Component TypeProtein
Sequence Length979 aa

Mast/stem cell growth factor receptor Kit

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Mast/stem cell growth factor receptor Kit, mapped to UniProt P05532. Sequence length is 979 aa.

Mapped IDP05532
Review nameMast/stem cell growth factor receptor Kit
OrganismMus musculus
Clinical Profile

Clinical Phase Distribution

1
Phase III
1
Phase II
Assay Mix

Activity Type Distribution

IC506.0
EC502.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL2037209 7.89 IC50 13.0 Preclinical
CHEMBL2037208 7.68 IC50 21.0 Preclinical
CHEMBL2037220 7.34 IC50 46.0 Preclinical
CHEMBL475251 7.34 EC50 46.0 Clinical
CHEMBL2037224 6.89 IC50 130.0 Preclinical
CHEMBL3265032 6.35 EC50 445.0 Clinical
CHEMBL2037211 6.3 IC50 500.0 Preclinical
CHEMBL2037226 6.04 IC50 910.0 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
3
6.0
1
6.5
2
7.0
2
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

4
Total Assays
8
Tested Compounds
1
Assay Types
Binding — 4 assays, 8 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 2 2 6.8
cell-based format 2 6 7.0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine