Regulator of G-protein signaling 8 · SINGLE PROTEIN · Homo sapiens
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P57771. Use UniProt P57771 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P57771 as the stable identity anchor, then attach disease evidence before program review.
Regulator of G-protein signaling 8
Review this target as Regulator of G-protein signaling 8, mapped to UniProt P57771. Sequence length is 180 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Regulator of G-protein signaling 8 as ChEMBL target CHEMBL2034803, mapped to UniProt P57771. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Regulator of G-protein signaling 8 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P57771 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Regulator of G-protein signaling 8 |
| UniProt Accession | P57771 |
| Component Type | Protein |
| Sequence Length | 180 aa |
Regulator of G-protein signaling 8
Review this target as Regulator of G-protein signaling 8, mapped to UniProt P57771. Sequence length is 180 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2037237 | 5.28 | IC50 | 5200.0 | Preclinical |
| CHEMBL2037236 | 5.25 | IC50 | 5600.0 | Preclinical |
| CHEMBL2037227 | 5.21 | IC50 | 6200.0 | Preclinical |
| CHEMBL2037232 | 5.15 | IC50 | 7100.0 | Preclinical |
| CHEMBL2037228 | 5.12 | IC50 | 7600.0 | Preclinical |
| CHEMBL2037235 | 5.12 | IC50 | 7500.0 | Preclinical |
| CHEMBL2037365 | 5.11 | IC50 | 7700.0 | Preclinical |
| CHEMBL2037358 | 5.08 | IC50 | 8400.0 | Preclinical |
| CHEMBL2037362 | 5.02 | IC50 | 9500.0 | Preclinical |
| CHEMBL2037354 | 5.0 | IC50 | 9900.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 40 | 4.8 |