Taste receptor type 2 member 31 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P59538. Use UniProt P59538 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P59538 as the stable identity anchor, then attach disease evidence before program review.
Taste receptor type 2 member 31
Review this target as Taste receptor type 2 member 31, mapped to UniProt P59538. Sequence length is 309 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Taste receptor type 2 member 31 as ChEMBL target CHEMBL2034804, mapped to UniProt P59538. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Taste receptor type 2 member 31 is the right protein anchor across sources, using UniProt P59538 as the stable mapping.
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| Preferred Name | Taste receptor type 2 member 31 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P59538 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Taste receptor type 2 member 31 |
| UniProt Accession | P59538 |
| Component Type | Protein |
| Sequence Length | 309 aa |
Taste receptor type 2 member 31
Review this target as Taste receptor type 2 member 31, mapped to UniProt P59538. Sequence length is 309 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL434 | 8.31 | EC50 | 4.9 | Approved |
| CHEMBL490162 | 5.7 | IC50 | 2000.0 | Preclinical |
| CHEMBL210692 | 5.6 | IC50 | 2500.0 | Preclinical |
| CHEMBL448297 | 5.44 | IC50 | 3600.0 | Preclinical |
| CHEMBL3315351 | 5.1 | IC50 | 8000.0 | Preclinical |
| CHEMBL487601 | 4.95 | IC50 | 11300.0 | Preclinical |
| CHEMBL4440983 | 4.5 | EC50 | 31500.0 | Preclinical |
| CHEMBL4582048 | 4.5 | EC50 | 31500.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 69 | 8 | 5.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 5 | 5.4 |