Acidic mammalian chitinase · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q91XA9. Use UniProt Q91XA9 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q91XA9 as the stable identity anchor, then attach disease evidence before program review.
Acidic mammalian chitinase
Review this target as Acidic mammalian chitinase, mapped to UniProt Q91XA9. Sequence length is 473 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Acidic mammalian chitinase as ChEMBL target CHEMBL2052027, mapped to UniProt Q91XA9. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Acidic mammalian chitinase is the right protein anchor across sources, using UniProt Q91XA9 as the stable mapping.
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| Preferred Name | Acidic mammalian chitinase |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | Q91XA9 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Acidic mammalian chitinase |
| UniProt Accession | Q91XA9 |
| Component Type | Protein |
| Sequence Length | 473 aa |
Acidic mammalian chitinase
Review this target as Acidic mammalian chitinase, mapped to UniProt Q91XA9. Sequence length is 473 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4756869 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL4776610 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL4794014 | 8.68 | IC50 | 2.1 | Preclinical |
| CHEMBL4764430 | 8.26 | IC50 | 5.5 | Preclinical |
| CHEMBL4788866 | 8.24 | Ki | 5.7 | Clinical |
| CHEMBL4084573 | 8.21 | IC50 | 6.2 | Preclinical |
| CHEMBL4789376 | 8.17 | IC50 | 6.7 | Preclinical |
| CHEMBL4749391 | 8.11 | IC50 | 7.8 | Preclinical |
| CHEMBL4755139 | 8.11 | IC50 | 7.7 | Preclinical |
| CHEMBL4788866 | 8.11 | IC50 | 7.8 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 63 | 7.0 |
| assay format | 2 | 4 | 5.4 |
| single protein format | 1 | 20 | 5.9 |