Dual specificity testis-specific protein kinase 2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q96S53. Use UniProt Q96S53 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q96S53 as the stable identity anchor, then attach disease evidence before program review.
Dual specificity testis-specific protein kinase 2
Review this target as Dual specificity testis-specific protein kinase 2, mapped to UniProt Q96S53. Sequence length is 571 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Dual specificity testis-specific protein kinase 2 as ChEMBL target CHEMBL2069163, mapped to UniProt Q96S53. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Dual specificity testis-specific protein kinase 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q96S53 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Dual specificity testis-specific protein kinase 2 |
| UniProt Accession | Q96S53 |
| Component Type | Protein |
| Sequence Length | 571 aa |
Dual specificity testis-specific protein kinase 2
Review this target as Dual specificity testis-specific protein kinase 2, mapped to UniProt Q96S53. Sequence length is 571 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3752910 | 9.11 | Kd | 0.772 | Preclinical |
| CHEMBL1738757 | 8.7 | Kd | 2.0 | Clinical |
| CHEMBL5653589 | 8.46 | Kd | 3.488 | Preclinical |
| CHEMBL3991933 | 7.75 | Kd | 18.0 | Preclinical |
| CHEMBL2070615 | 6.6 | IC50 | 252.0 | Preclinical |
| CHEMBL2070613 | 6.38 | IC50 | 415.0 | Preclinical |
| CHEMBL2070614 | 6.38 | IC50 | 415.0 | Preclinical |
| CHEMBL2070616 | 6.21 | IC50 | 612.0 | Preclinical |
| CHEMBL4088216 | 6.0 | IC50 | 1000.0 | Preclinical |
| CHEMBL4097778 | 6.0 | IC50 | 1000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 12 | 11 | 6.6 |
| subcellular format | 1 | 2 | 8.2 |