Monocarboxylate transporter 4 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt O15427. Use UniProt O15427 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O15427 as the stable identity anchor, then attach disease evidence before program review.
Monocarboxylate transporter 4
Review this target as Monocarboxylate transporter 4, mapped to UniProt O15427. Sequence length is 465 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Monocarboxylate transporter 4 as ChEMBL target CHEMBL2073663, mapped to UniProt O15427. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Monocarboxylate transporter 4 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | O15427 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Monocarboxylate transporter 4 |
| UniProt Accession | O15427 |
| Component Type | Protein |
| Sequence Length | 465 aa |
Monocarboxylate transporter 4
Review this target as Monocarboxylate transporter 4, mapped to UniProt O15427. Sequence length is 465 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5419465 | 9.64 | IC50 | 0.23 | Preclinical |
| CHEMBL5399511 | 9.54 | IC50 | 0.29 | Preclinical |
| CHEMBL5268154 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL5937220 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL5556465 | 9.49 | IC50 | 0.32 | Preclinical |
| CHEMBL5562055 | 9.46 | IC50 | 0.35 | Preclinical |
| CHEMBL5789173 | 9.46 | IC50 | 0.35 | Preclinical |
| CHEMBL5960010 | 9.46 | IC50 | 0.35 | Preclinical |
| CHEMBL5267318 | 9.44 | IC50 | 0.36 | Preclinical |
| CHEMBL5562438 | 9.44 | IC50 | 0.36 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 31 | 347 | 7.3 |
| single protein format | 14 | 25 | 7.1 |
| assay format | 4 | 82 | 6.9 |
| cell membrane format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 5 | 6.7 |