ATP-binding cassette sub-family C member 2 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q63120. Use UniProt Q63120 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q63120 as the stable identity anchor, then attach disease evidence before program review.
ATP-binding cassette sub-family C member 2
Review this target as ATP-binding cassette sub-family C member 2, mapped to UniProt Q63120. Sequence length is 1541 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats ATP-binding cassette sub-family C member 2 as ChEMBL target CHEMBL2073676, mapped to UniProt Q63120. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether ATP-binding cassette sub-family C member 2 is the right protein anchor across sources, using UniProt Q63120 as the stable mapping.
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| Preferred Name | ATP-binding cassette sub-family C member 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q63120 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | ATP-binding cassette sub-family C member 2 |
| UniProt Accession | Q63120 |
| Component Type | Protein |
| Sequence Length | 1541 aa |
ATP-binding cassette sub-family C member 2
Review this target as ATP-binding cassette sub-family C member 2, mapped to UniProt Q63120. Sequence length is 1541 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2074809 | 7.34 | Ki | 46.1 | Preclinical |
| CHEMBL3038248 | 7.0 | IC50 | 100.0 | Preclinical |
| CHEMBL2074720 | 6.92 | IC50 | 120.0 | Preclinical |
| CHEMBL495936 | 6.7 | IC50 | 200.0 | Preclinical |
| CHEMBL441687 | 6.08 | Ki | 840.0 | Clinical |
| CHEMBL1646 | 6.0 | Ki | 1000.0 | Approved |
| CHEMBL2369949 | 6.0 | Ki | 1010.0 | Preclinical |
| CHEMBL2075009 | 5.99 | Ki | 1030.0 | Preclinical |
| CHEMBL1743143 | 5.79 | Ki | 1620.0 | Preclinical |
| CHEMBL160 | 5.71 | Ki | 1960.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 66 | 64 | 5.1 |
| organism-based format | 32 | 0 | — |
| cell-based format | 19 | 1 | 4.9 |
| assay format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 2 | 4.1 |
| subcellular format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 2 | 6 | 4.3 |