Use UniProt Q62633 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL2073686 Target Snapshot
Ileal sodium/bile acid cotransporter · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-15Protein identity stays anchored to UniProt Q62633. Use UniProt Q62633 as the stable identity anchor, then attach disease evidence before program review.
Ileal sodium/bile acid cotransporter
Review this target as Ileal sodium/bile acid cotransporter, mapped to UniProt Q62633. Sequence length is 348 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Ileal sodium/bile acid cotransporter as ChEMBL target CHEMBL2073686, mapped to UniProt Q62633. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Ileal sodium/bile acid cotransporter |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q62633 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Ileal sodium/bile acid cotransporter |
| UniProt Accession | Q62633 |
| Component Type | Protein |
| Sequence Length | 348 aa |
Ileal sodium/bile acid cotransporter
How to read this target
Review this target as Ileal sodium/bile acid cotransporter, mapped to UniProt Q62633. Sequence length is 348 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2387397 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL2385105 | 9.05 | IC50 | 0.9 | Preclinical |
| CHEMBL2387408 | 8.72 | IC50 | 1.9 | Clinical |
| CHEMBL2387399 | 8.64 | IC50 | 2.3 | Preclinical |
| CHEMBL332370 | 7.66 | IC50 | 22.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Functional — 2 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 2 | 0 | — |
Binding — 1 assays, 5 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 5 | 8.8 |