Activated CDC42 kinase 1 · SINGLE PROTEIN · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt O54967. Use UniProt O54967 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O54967 as the stable identity anchor, then attach disease evidence before program review.
Activated CDC42 kinase 1
Review this target as Activated CDC42 kinase 1, mapped to UniProt O54967. Sequence length is 1055 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Activated CDC42 kinase 1 as ChEMBL target CHEMBL2079848, mapped to UniProt O54967. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Activated CDC42 kinase 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | O54967 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Activated CDC42 kinase 1 |
| UniProt Accession | O54967 |
| Component Type | Protein |
| Sequence Length | 1055 aa |
Activated CDC42 kinase 1
Review this target as Activated CDC42 kinase 1, mapped to UniProt O54967. Sequence length is 1055 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2087873 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL2087874 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL2087875 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL2087655 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL2087660 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL2087662 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL2087666 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL247479 | 7.52 | IC50 | 30.0 | Preclinical |
| CHEMBL2087654 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL2087664 | 7.4 | IC50 | 40.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 3 | 40 | 6.7 |