Carboxypeptidase A1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P15085. Use UniProt P15085 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P15085 as the stable identity anchor, then attach disease evidence before program review.
Carboxypeptidase A1
Review this target as Carboxypeptidase A1, mapped to UniProt P15085. Sequence length is 419 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Carboxypeptidase A1 as ChEMBL target CHEMBL2088, mapped to UniProt P15085. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Carboxypeptidase A1 is the right protein anchor across sources, using UniProt P15085 as the stable mapping.
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| Preferred Name | Carboxypeptidase A1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P15085 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Carboxypeptidase A1 |
| UniProt Accession | P15085 |
| Component Type | Protein |
| Sequence Length | 419 aa |
Carboxypeptidase A1
Review this target as Carboxypeptidase A1, mapped to UniProt P15085. Sequence length is 419 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4460840 | 10.4 | Ki | 0.04 | Preclinical |
| CHEMBL4445882 | 10.15 | Ki | 0.07 | Preclinical |
| CHEMBL4436298 | 10.1 | Ki | 0.08 | Preclinical |
| CHEMBL4528407 | 10.06 | Ki | 0.087 | Preclinical |
| CHEMBL4483485 | 9.97 | Ki | 0.107 | Preclinical |
| CHEMBL4454162 | 9.89 | Ki | 0.1287 | Preclinical |
| CHEMBL4513310 | 9.52 | Ki | 0.3 | Preclinical |
| CHEMBL4532731 | 8.92 | Ki | 1.2 | Preclinical |
| CHEMBL4453900 | 8.77 | Ki | 1.7 | Preclinical |
| CHEMBL452077 | 8.7 | IC50 | 2.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 23 | 73 | 6.4 |
| cell-free format | 2 | 4 | 5.8 |
| assay format | 1 | 6 | 4.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 4 | 0 | — |