Estrogen receptor · PROTEIN FAMILY · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P06211. Use UniProt P06211 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P06211 as the stable identity anchor, then attach disease evidence before program review.
Estrogen receptor
Review this target as Estrogen receptor, mapped to UniProt P06211. Sequence length is 600 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Estrogen receptor as ChEMBL target CHEMBL2094114, mapped to UniProt P06211. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Estrogen receptor is the right protein anchor across sources, using UniProt P06211 as the stable mapping.
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| Preferred Name | Estrogen receptor |
| Target Type | PROTEIN FAMILY |
| Organism | Rattus norvegicus |
| UniProt | P06211 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Estrogen receptor |
| UniProt Accession | P06211 |
| Component Type | Protein |
| Sequence Length | 600 aa |
Estrogen receptor
Review this target as Estrogen receptor, mapped to UniProt P06211. Sequence length is 600 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL135 | 9.45 | IC50 | 0.354 | Approved |
| CHEMBL1627822 | 9.21 | Kd | 0.62 | Preclinical |
| CHEMBL1162 | 9.2 | Kd | 0.63 | Approved |
| CHEMBL81 | 8.73 | IC50 | 1.85 | Approved |
| CHEMBL9225 | 8.7 | IC50 | 2.0 | Approved |
| CHEMBL285536 | 8.54 | EC50 | 2.9 | Preclinical |
| CHEMBL415864 | 8.49 | EC50 | 3.2 | Preclinical |
| CHEMBL287352 | 8.48 | EC50 | 3.3 | Preclinical |
| CHEMBL103 | 8.41 | Kd | 3.9 | Approved |
| CHEMBL34648 | 8.35 | EC50 | 4.5 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| organism-based format | 168 | 0 | — |
| assay format | 104 | 0 | — |
| tissue-based format | 55 | 0 | — |
| cell-free format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 99 | 32 | 7.4 |
| assay format | 18 | 0 | — |
| cell-based format | 2 | 0 | — |