Adenosine A2 receptor · PROTEIN FAMILY · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P29276. Use UniProt P29276 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P29276 as the stable identity anchor, then attach disease evidence before program review.
Adenosine receptor A2b
Review this target as Adenosine A2 receptor, mapped to UniProt P29276. ChEMBL maps the protein component as Adenosine receptor A2b. Sequence length is 332 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Adenosine A2 receptor as ChEMBL target CHEMBL2094117, mapped to UniProt P29276. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Adenosine A2 receptor |
| Target Type | PROTEIN FAMILY |
| Organism | Rattus norvegicus |
| UniProt | P29276 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Adenosine receptor A2b |
| UniProt Accession | P29276 |
| Component Type | Protein |
| Sequence Length | 332 aa |
Adenosine receptor A2b
Review this target as Adenosine A2 receptor, mapped to UniProt P29276. ChEMBL maps the protein component as Adenosine receptor A2b. Sequence length is 332 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2113405 | 9.3 | Ki | 0.5 | Preclinical |
| CHEMBL2113404 | 9.22 | Ki | 0.6 | Preclinical |
| CHEMBL16687 | 9.14 | Ki | 0.73 | Preclinical |
| CHEMBL2094083 | 9.05 | Ki | 0.9 | Preclinical |
| CHEMBL2113497 | 9.05 | Ki | 0.9 | Preclinical |
| CHEMBL27508 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL610440 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL2113412 | 9.0 | Ki | 1.0 | Preclinical |
| CHEMBL68738 | 8.96 | Ki | 1.1 | Preclinical |
| CHEMBL2113501 | 8.96 | Ki | 1.1 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell membrane format | 60 | 411 | 6.1 |
| protein format | 31 | 162 | 6.2 |
| assay format | 29 | 266 | 6.3 |
| tissue-based format | 17 | 215 | 6.3 |
| cell-based format | 7 | 56 | 5.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 8 | 6 | 5.7 |
| tissue-based format | 4 | 24 | 6.5 |
| cell membrane format | 3 | 15 | 4.8 |
| cell-based format | 3 | 14 | 6.5 |