Cysteinyl leukotriene receptor · PROTEIN FAMILY · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9Y271. Use UniProt Q9Y271 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9Y271 as the stable identity anchor, then attach disease evidence before program review.
Cysteinyl leukotriene receptor 1
Review this target as Cysteinyl leukotriene receptor, mapped to UniProt Q9Y271. ChEMBL maps the protein component as Cysteinyl leukotriene receptor 1. Sequence length is 337 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cysteinyl leukotriene receptor as ChEMBL target CHEMBL2094254, mapped to UniProt Q9Y271. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cysteinyl leukotriene receptor |
| Target Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
| UniProt | Q9Y271 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cysteinyl leukotriene receptor 1 |
| UniProt Accession | Q9Y271 |
| Component Type | Protein |
| Sequence Length | 337 aa |
Cysteinyl leukotriene receptor 1
Review this target as Cysteinyl leukotriene receptor, mapped to UniProt Q9Y271. ChEMBL maps the protein component as Cysteinyl leukotriene receptor 1. Sequence length is 337 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL354129 | 10.51 | IC50 | 0.031 | Preclinical |
| CHEMBL21333 | 10.36 | IC50 | 0.044 | Approved |
| CHEMBL171021 | 10.22 | IC50 | 0.06 | Preclinical |
| CHEMBL299837 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL169790 | 9.96 | IC50 | 0.11 | Preclinical |
| CHEMBL354530 | 9.85 | IC50 | 0.14 | Preclinical |
| CHEMBL170191 | 9.8 | IC50 | 0.16 | Preclinical |
| CHEMBL343934 | 9.77 | IC50 | 0.17 | Preclinical |
| CHEMBL344180 | 9.72 | IC50 | 0.19 | Preclinical |
| CHEMBL313187 | 9.7 | IC50 | 0.2 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 16 | 171 | 7.3 |
| organism-based format | 15 | 0 | — |
| assay format | 5 | 20 | 6.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 8 | 122 | 8.4 |
| assay format | 4 | 11 | 5.8 |
| cell membrane format | 3 | 88 | 6.2 |
| protein format | 2 | 11 | 7.5 |