Peroxisome proliferator-activated receptor gamma/Nuclear receptor coactivator 1 · PROTEIN-PROTEIN INTERACTION · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P37231. Use UniProt P37231 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P37231 as the stable identity anchor, then attach disease evidence before program review.
Peroxisome proliferator-activated receptor gamma
Review this target as Peroxisome proliferator-activated receptor gamma/Nuclear receptor coactivator 1, mapped to UniProt P37231. ChEMBL maps the protein component as Peroxisome proliferator-activated receptor gamma. Sequence length is 505 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Peroxisome proliferator-activated receptor gamma/Nuclear receptor coactivator 1 as ChEMBL target CHEMBL2095162, mapped to UniProt P37231. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Peroxisome proliferator-activated receptor gamma/Nuclear receptor coactivator 1 |
| Target Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
| UniProt | P37231 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Peroxisome proliferator-activated receptor gamma |
| UniProt Accession | P37231 |
| Component Type | Protein |
| Sequence Length | 505 aa |
Peroxisome proliferator-activated receptor gamma
Review this target as Peroxisome proliferator-activated receptor gamma/Nuclear receptor coactivator 1, mapped to UniProt P37231. ChEMBL maps the protein component as Peroxisome proliferator-activated receptor gamma. Sequence length is 505 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL405110 | 6.02 | EC50 | 958.0 | Approved |
| CHEMBL1471189 | 6.0 | EC50 | 1003.0 | Preclinical |
| CHEMBL1331930 | 5.79 | EC50 | 1607.0 | Preclinical |
| CHEMBL1386916 | 5.74 | EC50 | 1811.0 | Preclinical |
| CHEMBL1388589 | 5.71 | EC50 | 1972.0 | Preclinical |
| CHEMBL1427926 | 5.7 | EC50 | 2003.0 | Preclinical |
| CHEMBL1613238 | 5.69 | EC50 | 2045.0 | Preclinical |
| CHEMBL1349621 | 5.64 | EC50 | 2284.0 | Preclinical |
| CHEMBL1538790 | 5.57 | EC50 | 2718.0 | Preclinical |
| CHEMBL1579464 | 5.57 | EC50 | 2680.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 1 | 194 | 4.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 89 | 4.6 |