Dopamine receptors; D2 & D3 · SELECTIVITY GROUP · Homo sapiens
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As of 2026-09-14Dopamine receptors; D2 & D3 shows approved-linked disease relevance led by Nausea and vomiting. 5 more disease programs remain visible in the same review block. 1 linked drug keeps the current disease frame grounded. Protein identity stays anchored to UniProt P14416. Start with Nausea and vomiting, then reuse UniProt P14416 as the stable protein anchor across project notes and exports.
Start with Nausea and vomiting, then reuse UniProt P14416 as the stable protein anchor across project notes and exports.
Dopamine receptors; D2 & D3 shows approved-linked disease relevance led by Nausea and vomiting. 5 more disease programs remain visible in the same review block. 1 linked drug remains visible in the same block.
Start review with Nausea and vomiting because it currently carries approved-linked support. Linked drugs include AMISULPRIDE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
Disease source · ChEMBL drug mechanism + indication proxyD(2) dopamine receptor
Review this target as Dopamine receptors; D2 & D3, mapped to UniProt P14416. ChEMBL maps the protein component as D(2) dopamine receptor. Sequence length is 443 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Dopamine receptors; D2 & D3 as ChEMBL target CHEMBL2095169, mapped to UniProt P14416. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
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Start here when your first question is whether Dopamine receptors; D2 & D3 is the right protein anchor across sources, using UniProt P14416 as the stable mapping.
Jump to Protein ContextUse this block first when you need to confirm why Nausea and vomiting is currently framed as approved-linked support. It currently carries 1 linked drug in the same disease frame.
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| Preferred Name | Dopamine receptors; D2 & D3 |
| Target Type | SELECTIVITY GROUP |
| Organism | Homo sapiens |
| UniProt | P14416 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | D(2) dopamine receptor |
| UniProt Accession | P14416 |
| Component Type | Protein |
| Sequence Length | 443 aa |
D(2) dopamine receptor
Review this target as Dopamine receptors; D2 & D3, mapped to UniProt P14416. ChEMBL maps the protein component as D(2) dopamine receptor. Sequence length is 443 aa.
Open Targets-ready disease context using the current target-indication evidence contract.
Dopamine receptors; D2 & D3 shows approved-linked disease relevance led by Nausea and vomiting. 5 more disease programs remain visible in the same review block.
Start review with Nausea and vomiting because it currently carries approved-linked support. Linked drugs include AMISULPRIDE. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 36 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 6 | 0 | — |
| cell-based format | 1 | 0 | — |