Protein farnesyltransferase · PROTEIN COMPLEX · Bos taurus
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As of 2026-09-13Protein identity stays anchored to UniProt P29702. Use UniProt P29702 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P29702 as the stable identity anchor, then attach disease evidence before program review.
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Review this target as Protein farnesyltransferase, mapped to UniProt P29702. ChEMBL maps the protein component as Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha. Sequence length is 375 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Protein farnesyltransferase as ChEMBL target CHEMBL2095178, mapped to UniProt P29702. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Protein farnesyltransferase |
| Target Type | PROTEIN COMPLEX |
| Organism | Bos taurus |
| UniProt | P29702 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha |
| UniProt Accession | P29702 |
| Component Type | Protein |
| Sequence Length | 375 aa |
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Review this target as Protein farnesyltransferase, mapped to UniProt P29702. ChEMBL maps the protein component as Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha. Sequence length is 375 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL108161 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL333575 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL123019 | 10.0 | IC50 | 0.1 | Preclinical |
| CHEMBL440564 | 9.82 | IC50 | 0.15 | Preclinical |
| CHEMBL41515 | 9.8 | IC50 | 0.16 | Preclinical |
| CHEMBL23460 | 9.77 | IC50 | 0.17 | Preclinical |
| CHEMBL41951 | 9.74 | IC50 | 0.18 | Preclinical |
| CHEMBL37194 | 9.74 | IC50 | 0.18 | Preclinical |
| CHEMBL23155 | 9.72 | IC50 | 0.19 | Preclinical |
| CHEMBL41748 | 9.7 | IC50 | 0.2 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 49 | 298 | 7.8 |
| assay format | 9 | 88 | 7.6 |
| cell-based format | 3 | 17 | 7.5 |
| tissue-based format | 1 | 15 | 5.6 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 22 | 8.0 |