Opioid receptor · PROTEIN FAMILY · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt P42866. Use UniProt P42866 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P42866 as the stable identity anchor, then attach disease evidence before program review.
Mu-type opioid receptor
Review this target as Opioid receptor, mapped to UniProt P42866. ChEMBL maps the protein component as Mu-type opioid receptor. Sequence length is 398 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Opioid receptor as ChEMBL target CHEMBL2095192, mapped to UniProt P42866. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Opioid receptor |
| Target Type | PROTEIN FAMILY |
| Organism | Mus musculus |
| UniProt | P42866 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Mu-type opioid receptor |
| UniProt Accession | P42866 |
| Component Type | Protein |
| Sequence Length | 398 aa |
Mu-type opioid receptor
Review this target as Opioid receptor, mapped to UniProt P42866. ChEMBL maps the protein component as Mu-type opioid receptor. Sequence length is 398 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL415006 | 9.52 | Ki | 0.3 | Preclinical |
| CHEMBL340032 | 9.44 | IC50 | 0.36 | Preclinical |
| CHEMBL386810 | 9.3 | Ki | 0.5 | Preclinical |
| CHEMBL409172 | 8.96 | Ki | 1.1 | Preclinical |
| CHEMBL610531 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL1790710 | 8.57 | IC50 | 2.7 | Preclinical |
| CHEMBL31421 | 8.55 | IC50 | 2.8 | Preclinical |
| CHEMBL414603 | 8.48 | Ki | 3.3 | Preclinical |
| CHEMBL611140 | 8.2 | Ki | 6.3 | Preclinical |
| CHEMBL293145 | 8.15 | IC50 | 7.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 15 | 9 | 7.5 |
| assay format | 14 | 10 | 7.4 |
| organism-based format | 8 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 19 | 30 | 6.4 |
| assay format | 8 | 0 | — |
| cell-based format | 4 | 7 | 8.0 |
| tissue-based format | 3 | 2 | 7.6 |
| organism-based format | 2 | 0 | — |