Coagulation factor VII/tissue factor · PROTEIN COMPLEX · Homo sapiens
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P08709. Use UniProt P08709 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P08709 as the stable identity anchor, then attach disease evidence before program review.
Coagulation factor VII
Review this target as Coagulation factor VII/tissue factor, mapped to UniProt P08709. ChEMBL maps the protein component as Coagulation factor VII. Sequence length is 466 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Coagulation factor VII/tissue factor as ChEMBL target CHEMBL2095194, mapped to UniProt P08709. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Coagulation factor VII/tissue factor is the right protein anchor across sources, using UniProt P08709 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Coagulation factor VII/tissue factor |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | P08709 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Coagulation factor VII |
| UniProt Accession | P08709 |
| Component Type | Protein |
| Sequence Length | 466 aa |
Coagulation factor VII
Review this target as Coagulation factor VII/tissue factor, mapped to UniProt P08709. ChEMBL maps the protein component as Coagulation factor VII. Sequence length is 466 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL505189 | 11.0 | IC50 | 0.01 | Preclinical |
| CHEMBL505190 | 11.0 | IC50 | 0.01 | Preclinical |
| CHEMBL484616 | 10.96 | IC50 | 0.011 | Preclinical |
| CHEMBL506771 | 10.96 | IC50 | 0.011 | Preclinical |
| CHEMBL526504 | 10.96 | IC50 | 0.011 | Preclinical |
| CHEMBL523251 | 10.92 | IC50 | 0.012 | Preclinical |
| CHEMBL520364 | 10.89 | IC50 | 0.013 | Preclinical |
| CHEMBL506772 | 10.85 | IC50 | 0.014 | Preclinical |
| CHEMBL524370 | 10.7 | IC50 | 0.02 | Preclinical |
| CHEMBL524732 | 10.68 | IC50 | 0.021 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 35 | 421 | 7.2 |
| assay format | 4 | 18 | 3.9 |
| single protein format | 2 | 14 | 4.3 |
| cell-free format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-free format | 9 | 0 | — |
| organism-based format | 3 | 0 | — |
| assay format | 1 | 0 | — |
| tissue-based format | 1 | 0 | — |