Histone deacetylase · PROTEIN FAMILY · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q6P6W3. Use UniProt Q6P6W3 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q6P6W3 as the stable identity anchor, then attach disease evidence before program review.
Histone deacetylase 3
Review this target as Histone deacetylase, mapped to UniProt Q6P6W3. ChEMBL maps the protein component as Histone deacetylase 3. Sequence length is 428 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Histone deacetylase as ChEMBL target CHEMBL2095943, mapped to UniProt Q6P6W3. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Histone deacetylase |
| Target Type | PROTEIN FAMILY |
| Organism | Rattus norvegicus |
| UniProt | Q6P6W3 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Histone deacetylase 3 |
| UniProt Accession | Q6P6W3 |
| Component Type | Protein |
| Sequence Length | 428 aa |
Histone deacetylase 3
Review this target as Histone deacetylase, mapped to UniProt Q6P6W3. ChEMBL maps the protein component as Histone deacetylase 3. Sequence length is 428 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL3319223 | 8.47 | IC50 | 3.4 | Preclinical |
| CHEMBL3319215 | 8.44 | IC50 | 3.6 | Preclinical |
| CHEMBL1790587 | 8.2 | IC50 | 6.29 | Preclinical |
| CHEMBL99 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL3763388 | 7.75 | IC50 | 18.0 | Preclinical |
| CHEMBL3764525 | 7.68 | IC50 | 21.0 | Preclinical |
| CHEMBL360194 | 7.67 | IC50 | 21.2 | Preclinical |
| CHEMBL435643 | 7.42 | IC50 | 38.0 | Preclinical |
| CHEMBL203207 | 7.4 | IC50 | 40.0 | Preclinical |
| CHEMBL140000 | 7.34 | IC50 | 46.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 18 | 31 | 6.8 |
| cell-based format | 4 | 2 | 8.5 |
| tissue-based format | 2 | 38 | 6.5 |
| protein format | 1 | 4 | 6.5 |