Serotonin 2 (5-HT2) receptor · PROTEIN FAMILY · Mus musculus
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As of 2026-09-14Protein identity stays anchored to UniProt Q02152. Use UniProt Q02152 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q02152 as the stable identity anchor, then attach disease evidence before program review.
5-hydroxytryptamine receptor 2B
Review this target as Serotonin 2 (5-HT2) receptor, mapped to UniProt Q02152. ChEMBL maps the protein component as 5-hydroxytryptamine receptor 2B. Sequence length is 479 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serotonin 2 (5-HT2) receptor as ChEMBL target CHEMBL2096671, mapped to UniProt Q02152. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Serotonin 2 (5-HT2) receptor is the right protein anchor across sources, using UniProt Q02152 as the stable mapping.
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| Preferred Name | Serotonin 2 (5-HT2) receptor |
| Target Type | PROTEIN FAMILY |
| Organism | Mus musculus |
| UniProt | Q02152 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | 5-hydroxytryptamine receptor 2B |
| UniProt Accession | Q02152 |
| Component Type | Protein |
| Sequence Length | 479 aa |
5-hydroxytryptamine receptor 2B
Review this target as Serotonin 2 (5-HT2) receptor, mapped to UniProt Q02152. ChEMBL maps the protein component as 5-hydroxytryptamine receptor 2B. Sequence length is 479 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL141319 | 9.54 | IC50 | 0.29 | Preclinical |
| CHEMBL343838 | 9.46 | IC50 | 0.35 | Preclinical |
| CHEMBL267777 | 9.09 | Ki | 0.82 | Clinical |
| CHEMBL36645 | 9.09 | Ki | 0.82 | Preclinical |
| CHEMBL142850 | 9.07 | IC50 | 0.85 | Preclinical |
| CHEMBL38078 | 9.07 | Ki | 0.85 | Preclinical |
| CHEMBL343228 | 8.92 | IC50 | 1.2 | Preclinical |
| CHEMBL141438 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL142456 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL141392 | 8.82 | IC50 | 1.5 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 4 | 102 | 7.2 |
| tissue-based format | 4 | 6 | 4.9 |
| organism-based format | 2 | 0 | — |
| assay format | 1 | 36 | 7.4 |