Small conductance calcium-activated potassium channel · PROTEIN FAMILY · Rattus norvegicus
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P70604. Use UniProt P70604 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P70604 as the stable identity anchor, then attach disease evidence before program review.
Small conductance calcium-activated potassium channel protein 2
Review this target as Small conductance calcium-activated potassium channel, mapped to UniProt P70604. ChEMBL maps the protein component as Small conductance calcium-activated potassium channel protein 2. Sequence length is 580 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Small conductance calcium-activated potassium channel as ChEMBL target CHEMBL2096673, mapped to UniProt P70604. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Small conductance calcium-activated potassium channel is the right protein anchor across sources, using UniProt P70604 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Small conductance calcium-activated potassium channel |
| Target Type | PROTEIN FAMILY |
| Organism | Rattus norvegicus |
| UniProt | P70604 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Small conductance calcium-activated potassium channel protein 2 |
| UniProt Accession | P70604 |
| Component Type | Protein |
| Sequence Length | 580 aa |
Small conductance calcium-activated potassium channel protein 2
Review this target as Small conductance calcium-activated potassium channel, mapped to UniProt P70604. ChEMBL maps the protein component as Small conductance calcium-activated potassium channel protein 2. Sequence length is 580 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4128926 | 10.92 | IC50 | 0.012 | Preclinical |
| CHEMBL3774478 | 10.8 | IC50 | 0.016 | Preclinical |
| CHEMBL420873 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL117908 | 8.52 | IC50 | 3.0 | Preclinical |
| CHEMBL184300 | 8.05 | IC50 | 9.0 | Preclinical |
| CHEMBL185146 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL181911 | 7.92 | IC50 | 12.0 | Preclinical |
| CHEMBL183644 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL184858 | 7.8 | IC50 | 16.0 | Preclinical |
| CHEMBL397282 | 7.64 | Ki | 23.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 12 | 29 | 5.9 |
| protein format | 7 | 8 | 5.7 |
| tissue-based format | 4 | 1 | 10.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 5 | 58 | 6.3 |
| assay format | 1 | 0 | — |
| tissue-based format | 1 | 31 | 6.8 |