Vanilloid receptor · PROTEIN FAMILY · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q9ERZ8. Use UniProt Q9ERZ8 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9ERZ8 as the stable identity anchor, then attach disease evidence before program review.
Transient receptor potential cation channel subfamily V member 4
Review this target as Vanilloid receptor, mapped to UniProt Q9ERZ8. ChEMBL maps the protein component as Transient receptor potential cation channel subfamily V member 4. Sequence length is 871 aa.
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This review treats Vanilloid receptor as ChEMBL target CHEMBL2096684, mapped to UniProt Q9ERZ8. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Vanilloid receptor |
| Target Type | PROTEIN FAMILY |
| Organism | Rattus norvegicus |
| UniProt | Q9ERZ8 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Transient receptor potential cation channel subfamily V member 4 |
| UniProt Accession | Q9ERZ8 |
| Component Type | Protein |
| Sequence Length | 871 aa |
Transient receptor potential cation channel subfamily V member 4
Review this target as Vanilloid receptor, mapped to UniProt Q9ERZ8. ChEMBL maps the protein component as Transient receptor potential cation channel subfamily V member 4. Sequence length is 871 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL415543 | 9.49 | IC50 | 0.32 | Preclinical |
| CHEMBL155433 | 9.34 | IC50 | 0.46 | Preclinical |
| CHEMBL154743 | 9.3 | IC50 | 0.5 | Preclinical |
| CHEMBL156041 | 9.26 | IC50 | 0.55 | Preclinical |
| CHEMBL267205 | 9.14 | IC50 | 0.72 | Preclinical |
| CHEMBL154990 | 9.02 | IC50 | 0.95 | Preclinical |
| CHEMBL155730 | 9.02 | IC50 | 0.95 | Preclinical |
| CHEMBL157962 | 8.92 | IC50 | 1.2 | Preclinical |
| CHEMBL17976 | 8.8 | EC50 | 1.6 | Clinical |
| CHEMBL422702 | 8.62 | IC50 | 2.4 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 31 | 148 | 6.3 |
| tissue-based format | 5 | 22 | 7.0 |