Use UniProt P30419 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL2096973 Target Snapshot
Peptide N-myristoyltransferase · PROTEIN FAMILY · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P30419. Use UniProt P30419 as the stable identity anchor, then attach disease evidence before program review.
Glycylpeptide N-tetradecanoyltransferase 1
Review this target as Peptide N-myristoyltransferase, mapped to UniProt P30419. ChEMBL maps the protein component as Glycylpeptide N-tetradecanoyltransferase 1. Sequence length is 496 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Peptide N-myristoyltransferase as ChEMBL target CHEMBL2096973, mapped to UniProt P30419. Disease framing currently uses the Open Targets-ready proxy contract.
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Open Review-ready CardBasic Information
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| Preferred Name | Peptide N-myristoyltransferase |
| Target Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
| UniProt | P30419 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Glycylpeptide N-tetradecanoyltransferase 1 |
| UniProt Accession | P30419 |
| Component Type | Protein |
| Sequence Length | 496 aa |
Glycylpeptide N-tetradecanoyltransferase 1
How to read this target
Review this target as Peptide N-myristoyltransferase, mapped to UniProt P30419. ChEMBL maps the protein component as Glycylpeptide N-tetradecanoyltransferase 1. Sequence length is 496 aa.
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL170807 | 9.41 | IC50 | 0.39 | Preclinical |
| CHEMBL173370 | 9.4 | IC50 | 0.4 | Preclinical |
| CHEMBL171506 | 9.24 | IC50 | 0.58 | Preclinical |
| CHEMBL170524 | 9.15 | IC50 | 0.71 | Preclinical |
| CHEMBL355497 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL422896 | 8.89 | IC50 | 1.3 | Preclinical |
| CHEMBL422746 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL355250 | 8.46 | IC50 | 3.5 | Preclinical |
| CHEMBL155301 | 8.43 | IC50 | 3.7 | Preclinical |
| CHEMBL155469 | 8.43 | IC50 | 3.7 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Binding — 43 assays, 91 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 43 | 91 | 6.0 |