Platelet-derived growth factor receptor · PROTEIN COMPLEX · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P05622. Use UniProt P05622 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P05622 as the stable identity anchor, then attach disease evidence before program review.
Platelet-derived growth factor receptor beta
Review this target as Platelet-derived growth factor receptor, mapped to UniProt P05622. ChEMBL maps the protein component as Platelet-derived growth factor receptor beta. Sequence length is 1098 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Platelet-derived growth factor receptor as ChEMBL target CHEMBL2096980, mapped to UniProt P05622. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Platelet-derived growth factor receptor is the right protein anchor across sources, using UniProt P05622 as the stable mapping.
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| Preferred Name | Platelet-derived growth factor receptor |
| Target Type | PROTEIN COMPLEX |
| Organism | Mus musculus |
| UniProt | P05622 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Platelet-derived growth factor receptor beta |
| UniProt Accession | P05622 |
| Component Type | Protein |
| Sequence Length | 1098 aa |
Platelet-derived growth factor receptor beta
Review this target as Platelet-derived growth factor receptor, mapped to UniProt P05622. ChEMBL maps the protein component as Platelet-derived growth factor receptor beta. Sequence length is 1098 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL301612 | 8.77 | IC50 | 1.7 | Preclinical |
| CHEMBL297523 | 8.77 | IC50 | 1.7 | Preclinical |
| CHEMBL112914 | 8.77 | IC50 | 1.7 | Preclinical |
| CHEMBL49120 | 8.74 | IC50 | 1.8 | Preclinical |
| CHEMBL388978 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL535 | 8.1 | IC50 | 8.0 | Approved |
| CHEMBL13976 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL13983 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL136106 | 7.51 | IC50 | 31.0 | Preclinical |
| CHEMBL13354 | 7.43 | IC50 | 37.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 11 | 30 | 5.9 |
| protein complex format | 10 | 75 | 5.9 |
| assay format | 1 | 26 | 6.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 13 | 20 | 6.6 |