Pancreatic elastase · PROTEIN FAMILY · Sus scrofa
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Move to another high-traffic target or paste a specific ChEMBL target ID.
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P08419. Use UniProt P08419 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P08419 as the stable identity anchor, then attach disease evidence before program review.
Chymotrypsin-like elastase family member 2A
Review this target as Pancreatic elastase, mapped to UniProt P08419. ChEMBL maps the protein component as Chymotrypsin-like elastase family member 2A. Sequence length is 269 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Pancreatic elastase as ChEMBL target CHEMBL2096984, mapped to UniProt P08419. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether Pancreatic elastase is the right protein anchor across sources, using UniProt P08419 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardVerify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | Pancreatic elastase |
| Target Type | PROTEIN FAMILY |
| Organism | Sus scrofa |
| UniProt | P08419 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Chymotrypsin-like elastase family member 2A |
| UniProt Accession | P08419 |
| Component Type | Protein |
| Sequence Length | 269 aa |
Chymotrypsin-like elastase family member 2A
Review this target as Pancreatic elastase, mapped to UniProt P08419. ChEMBL maps the protein component as Chymotrypsin-like elastase family member 2A. Sequence length is 269 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL130253 | 7.82 | Ki | 15.0 | Preclinical |
| CHEMBL131780 | 7.54 | Ki | 29.0 | Preclinical |
| CHEMBL337396 | 7.5 | Ki | 32.0 | Preclinical |
| CHEMBL130271 | 7.48 | Ki | 33.0 | Preclinical |
| CHEMBL339870 | 7.06 | Ki | 88.0 | Preclinical |
| CHEMBL131188 | 6.85 | Ki | 140.0 | Preclinical |
| CHEMBL130128 | 6.82 | Ki | 150.0 | Preclinical |
| CHEMBL2304256 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL310738 | 6.72 | IC50 | 190.0 | Preclinical |
| CHEMBL130718 | 6.62 | Ki | 240.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 50 | 66 | 5.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein format | 1 | 0 | — |