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Target Snapshot

CHEMBL2096986 Target Snapshot

Cholecystokinin receptor · PROTEIN FAMILY · Rattus norvegicus

223Compounds
18Assays
1Approved Drugs
132.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-13

Protein identity stays anchored to UniProt P30551. Use UniProt P30551 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P30551 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-13
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Cholecystokinin receptor as ChEMBL target CHEMBL2096986, mapped to UniProt P30551. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Cholecystokinin receptor
PROTEIN FAMILY · Rattus norvegicus
As of 2026-09-13
ChEMBL target ID
CHEMBL2096986
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-13
www.ebi.ac.uk
UniProt accession
P30551
Cholecystokinin receptor type A
UniProt accession via ChEMBL component mapping As of 2026-09-13
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-13
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

Choose the first block or source based on the question you are trying to answer.

Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Cholecystokinin receptor is the right protein anchor across sources, using UniProt P30551 as the stable mapping.

Jump to Protein Context
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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need the strongest disease program and evidence level in one place.

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelCholecystokinin receptor type A
UniProt AccessionP30551
Component TypeProtein
Sequence Length444 aa

Cholecystokinin receptor type A

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Cholecystokinin receptor, mapped to UniProt P30551. ChEMBL maps the protein component as Cholecystokinin receptor type A. Sequence length is 444 aa.

Mapped IDP30551
Review nameCholecystokinin receptor
OrganismRattus norvegicus
Clinical Profile

Clinical Phase Distribution

1
Approved
2
Phase II
Assay Mix

Activity Type Distribution

IC50132.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL9506 9.1 IC50 0.8 Clinical
CHEMBL384035 8.82 IC50 1.5 Preclinical
CHEMBL1907959 8.52 IC50 3.0 Preclinical
CHEMBL296718 8.4 IC50 4.0 Preclinical
CHEMBL1907960 8.38 IC50 4.2 Preclinical
CHEMBL1159915 8.3 IC50 5.0 Preclinical
CHEMBL47186 8.15 IC50 7.0 Preclinical
CHEMBL297534 8.12 IC50 7.5 Preclinical
CHEMBL1159912 8.0 IC50 10.0 Preclinical
CHEMBL2017835 7.77 IC50 17.02 Preclinical
Distribution

pChEMBL Value Distribution

17
5.0
21
5.5
9
6.0
13
6.5
7
7.0
7
7.5
6
8.0
2
8.5
1
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

18
Total Assays
114
Tested Compounds
2
Assay Types
Binding — 16 assays, 114 compounds
BAO Format Assays Compounds Avg pChEMBL
protein format 10 83 5.7
assay format 4 29 6.2
cell-based format 1 2 7.7
tissue-based format 1 0
Functional — 2 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 2 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine