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Target Snapshot

CHEMBL2111188 Target Snapshot

Mycobacterium tuberculosis H37Rv · ORGANISM · Mycobacterium tuberculosis H37Rv

276Compounds
18Assays
0Approved Drugs
0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Mycobacterium tuberculosis H37Rv shows approved-linked disease relevance led by drug-resistant tuberculosis. 3 more disease programs remain visible in the same review block. 1 linked drug keeps the current disease frame grounded. Use drug-resistant tuberculosis as the disease frame, then confirm a stable protein accession before cross-source reuse.

Review focus
Disease frame ready

Use drug-resistant tuberculosis as the disease frame, then confirm a stable protein accession before cross-source reuse.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14 1 linked drug
Open source guide
Disease program
drug-resistant tuberculosis

Mycobacterium tuberculosis H37Rv shows approved-linked disease relevance led by drug-resistant tuberculosis. 3 more disease programs remain visible in the same review block. 1 linked drug remains visible in the same block.

Start review with drug-resistant tuberculosis because it currently carries approved-linked support. Linked drugs include DELAMANID. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Disease source · ChEMBL drug mechanism + indication proxy
Approved-linked Open Targets-ready proxy 1 linked drug
Open disease block
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Mycobacterium tuberculosis H37Rv as ChEMBL target CHEMBL2111188. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Mycobacterium tuberculosis H37Rv
ORGANISM · Mycobacterium tuberculosis H37Rv
As of 2026-09-14
ChEMBL target ID
CHEMBL2111188
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

Start with the right source

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Need stable target naming and protein identity?
UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Mycobacterium tuberculosis H37Rv still has a stable protein naming contract across sources.

Jump to Protein Context
Need disease fit before discussing compounds?
Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

Use this block first when you need to confirm why drug-resistant tuberculosis is currently framed as approved-linked support. It currently carries 1 linked drug in the same disease frame.

Jump to Disease Context
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Evidence Card
Review-ready rationale with source-aware context

Open the one-page evidence card when you want the rationale, activity base, and attribution together.

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelMycobacterium tuberculosis H37Rv
UniProt AccessionN/A

Mycobacterium tuberculosis H37Rv

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Mycobacterium tuberculosis H37Rv.

Review nameMycobacterium tuberculosis H37Rv
OrganismMycobacterium tuberculosis H37Rv
Disease Relevance

Disease Relevance & Evidence Level

Open Targets-ready disease context using the current target-indication evidence contract.

Approved-linked Open Targets-ready proxy

Mycobacterium tuberculosis H37Rv shows approved-linked disease relevance led by drug-resistant tuberculosis. 3 more disease programs remain visible in the same review block.

Approved-linked Approved
drug-resistant tuberculosis
1 linked drug · 1 direct · 1 efficacy
Linked drugDELAMANID
Approved-linked Approved
multidrug-resistant tuberculosis
1 linked drug · 1 direct · 1 efficacy
Linked drugDELAMANID
Approved-linked Approved
tuberculosis
1 linked drug · 1 direct · 1 efficacy
Linked drugDELAMANID
Late clinical Phase III
pulmonary tuberculosis
1 linked drug · 1 direct · 1 efficacy
Linked drugDELAMANID
Source · ChEMBL drug mechanism + indication proxy
Review Cue

How to read disease relevance

Start review with drug-resistant tuberculosis because it currently carries approved-linked support. Linked drugs include DELAMANID. This disease block keeps the Open Targets-ready contract explicit while current evidence comes from ChEMBL mechanism and indication mappings.

Lead diseasedrug-resistant tuberculosis
Strongest levelApproved-linked
Block modeOpen Targets-ready proxy
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
0
7.5
0
8.0
0
8.5
0
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

18
Total Assays
0
Tested Compounds
2
Assay Types
Functional — 11 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 11 0
ADME — 7 assays, 0 compounds
BAO Format Assays Compounds Avg pChEMBL
organism-based format 7 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine