Cyclin-dependent kinase 7/ cyclin H · PROTEIN COMPLEX · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P51946. Use UniProt P51946 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P51946 as the stable identity anchor, then attach disease evidence before program review.
Cyclin-H
Review this target as Cyclin-dependent kinase 7/ cyclin H, mapped to UniProt P51946. ChEMBL maps the protein component as Cyclin-H. Sequence length is 323 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cyclin-dependent kinase 7/ cyclin H as ChEMBL target CHEMBL2111288, mapped to UniProt P51946. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cyclin-dependent kinase 7/ cyclin H |
| Target Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
| UniProt | P51946 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cyclin-H |
| UniProt Accession | P51946 |
| Component Type | Protein |
| Sequence Length | 323 aa |
Cyclin-H
Review this target as Cyclin-dependent kinase 7/ cyclin H, mapped to UniProt P51946. ChEMBL maps the protein component as Cyclin-H. Sequence length is 323 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL5088381 | 10.52 | Kd | 0.03 | Preclinical |
| CHEMBL5080711 | 10.22 | Kd | 0.06 | Preclinical |
| CHEMBL5090754 | 10.15 | Kd | 0.07 | Preclinical |
| CHEMBL4791134 | 10.15 | Kd | 0.07 | Preclinical |
| CHEMBL4786592 | 10.1 | Kd | 0.08 | Preclinical |
| CHEMBL4782954 | 10.1 | Kd | 0.08 | Preclinical |
| CHEMBL5083688 | 10.05 | Kd | 0.09 | Preclinical |
| CHEMBL4790490 | 10.0 | Kd | 0.1 | Preclinical |
| CHEMBL4779443 | 10.0 | Kd | 0.1 | Preclinical |
| CHEMBL4786320 | 9.82 | Kd | 0.15 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| protein complex format | 109 | 225 | 6.3 |
| cell-based format | 18 | 65 | 7.3 |
| assay format | 5 | 0 | — |