Platelet-derived growth factor receptor (PDGFr) · PROTEIN FAMILY · Rattus norvegicus
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As of 2026-09-13Protein identity stays anchored to UniProt P20786. Use UniProt P20786 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P20786 as the stable identity anchor, then attach disease evidence before program review.
Platelet-derived growth factor receptor alpha
Review this target as Platelet-derived growth factor receptor (PDGFr), mapped to UniProt P20786. ChEMBL maps the protein component as Platelet-derived growth factor receptor alpha. Sequence length is 1088 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Platelet-derived growth factor receptor (PDGFr) as ChEMBL target CHEMBL2111344, mapped to UniProt P20786. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Platelet-derived growth factor receptor (PDGFr) is the right protein anchor across sources, using UniProt P20786 as the stable mapping.
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| Preferred Name | Platelet-derived growth factor receptor (PDGFr) |
| Target Type | PROTEIN FAMILY |
| Organism | Rattus norvegicus |
| UniProt | P20786 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Platelet-derived growth factor receptor alpha |
| UniProt Accession | P20786 |
| Component Type | Protein |
| Sequence Length | 1088 aa |
Platelet-derived growth factor receptor alpha
Review this target as Platelet-derived growth factor receptor (PDGFr), mapped to UniProt P20786. ChEMBL maps the protein component as Platelet-derived growth factor receptor alpha. Sequence length is 1088 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL301612 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL297523 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL112914 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL134851 | 8.82 | IC50 | 1.5 | Preclinical |
| CHEMBL434448 | 8.34 | IC50 | 4.6 | Preclinical |
| CHEMBL49120 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL136332 | 7.27 | IC50 | 54.0 | Preclinical |
| CHEMBL136106 | 7.24 | IC50 | 58.0 | Preclinical |
| CHEMBL80873 | 6.89 | IC50 | 130.0 | Preclinical |
| CHEMBL153054 | 6.82 | IC50 | 150.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 7 | 17 | 6.6 |
| cell-based format | 2 | 3 | 8.0 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 6 | 34 | 5.7 |
| cell-based format | 3 | 5 | 8.0 |