Use UniProt P02554 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL2111354 Target Snapshot
Tubulin · PROTEIN FAMILY · Sus scrofa
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As of 2026-09-14Protein identity stays anchored to UniProt P02554. Use UniProt P02554 as the stable identity anchor, then attach disease evidence before program review.
Tubulin beta chain
Review this target as Tubulin, mapped to UniProt P02554. ChEMBL maps the protein component as Tubulin beta chain. Sequence length is 445 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Tubulin as ChEMBL target CHEMBL2111354, mapped to UniProt P02554. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Tubulin is the right protein anchor across sources, using UniProt P02554 as the stable mapping.
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Open Review-ready CardBasic Information
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| Preferred Name | Tubulin |
| Target Type | PROTEIN FAMILY |
| Organism | Sus scrofa |
| UniProt | P02554 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Tubulin beta chain |
| UniProt Accession | P02554 |
| Component Type | Protein |
| Sequence Length | 445 aa |
Tubulin beta chain
How to read this target
Review this target as Tubulin, mapped to UniProt P02554. ChEMBL maps the protein component as Tubulin beta chain. Sequence length is 445 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2181004 | 10.34 | Ki | 0.04603 | Preclinical |
| CHEMBL2181003 | 10.23 | Ki | 0.05848 | Preclinical |
| CHEMBL2181002 | 10.2 | Ki | 0.06368 | Preclinical |
| CHEMBL2181009 | 9.91 | Ki | 0.1219 | Preclinical |
| CHEMBL2181006 | 9.9 | Ki | 0.1268 | Preclinical |
| CHEMBL2181001 | 9.88 | Ki | 0.1312 | Preclinical |
| CHEMBL2181000 | 9.85 | Ki | 0.1426 | Preclinical |
| CHEMBL2181008 | 9.74 | Ki | 0.1832 | Preclinical |
| CHEMBL2180999 | 9.7 | Ki | 0.1982 | Preclinical |
| CHEMBL2181007 | 9.55 | Ki | 0.2799 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 321 assays, 335 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 188 | 218 | 5.6 |
| protein format | 112 | 79 | 5.6 |
| tissue-based format | 20 | 38 | 6.5 |
| cell-based format | 1 | 0 | — |
Functional — 9 assays, 31 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 9 | 31 | 5.7 |