Muscarinic acetylcholine receptor M1 and M3 · SELECTIVITY GROUP · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P20309. Use UniProt P20309 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P20309 as the stable identity anchor, then attach disease evidence before program review.
Muscarinic acetylcholine receptor M3
Review this target as Muscarinic acetylcholine receptor M1 and M3, mapped to UniProt P20309. ChEMBL maps the protein component as Muscarinic acetylcholine receptor M3. Sequence length is 590 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Muscarinic acetylcholine receptor M1 and M3 as ChEMBL target CHEMBL2111418, mapped to UniProt P20309. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Muscarinic acetylcholine receptor M1 and M3 |
| Target Type | SELECTIVITY GROUP |
| Organism | Homo sapiens |
| UniProt | P20309 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Muscarinic acetylcholine receptor M3 |
| UniProt Accession | P20309 |
| Component Type | Protein |
| Sequence Length | 590 aa |
Muscarinic acetylcholine receptor M3
Review this target as Muscarinic acetylcholine receptor M1 and M3, mapped to UniProt P20309. ChEMBL maps the protein component as Muscarinic acetylcholine receptor M3. Sequence length is 590 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL277642 | 6.76 | Kd | 175.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 11 | 0 | — |
| protein format | 6 | 0 | — |
| cell-based format | 5 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 1 | 6.8 |