Melanin-concentrating hormone receptor · PROTEIN FAMILY · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q969V1. Use UniProt Q969V1 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q969V1 as the stable identity anchor, then attach disease evidence before program review.
Melanin-concentrating hormone receptor 2
Review this target as Melanin-concentrating hormone receptor, mapped to UniProt Q969V1. ChEMBL maps the protein component as Melanin-concentrating hormone receptor 2. Sequence length is 340 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Melanin-concentrating hormone receptor as ChEMBL target CHEMBL2111437, mapped to UniProt Q969V1. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Melanin-concentrating hormone receptor is the right protein anchor across sources, using UniProt Q969V1 as the stable mapping.
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| Preferred Name | Melanin-concentrating hormone receptor |
| Target Type | PROTEIN FAMILY |
| Organism | Homo sapiens |
| UniProt | Q969V1 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Melanin-concentrating hormone receptor 2 |
| UniProt Accession | Q969V1 |
| Component Type | Protein |
| Sequence Length | 340 aa |
Melanin-concentrating hormone receptor 2
Review this target as Melanin-concentrating hormone receptor, mapped to UniProt Q969V1. ChEMBL maps the protein component as Melanin-concentrating hormone receptor 2. Sequence length is 340 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL179501 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL214585 | 7.82 | IC50 | 15.0 | Preclinical |
| CHEMBL214731 | 7.6 | IC50 | 25.0 | Preclinical |
| CHEMBL215661 | 7.58 | IC50 | 26.0 | Preclinical |
| CHEMBL214021 | 7.54 | IC50 | 29.0 | Preclinical |
| CHEMBL216554 | 7.46 | IC50 | 35.0 | Preclinical |
| CHEMBL266725 | 7.36 | IC50 | 44.0 | Preclinical |
| CHEMBL386281 | 7.34 | IC50 | 46.0 | Preclinical |
| CHEMBL216104 | 7.24 | IC50 | 57.0 | Preclinical |
| CHEMBL274168 | 7.18 | IC50 | 66.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 4 | 37 | 6.6 |
| tissue-based format | 1 | 0 | — |