Peroxisome proliferator-activated receptor alpha · SINGLE PROTEIN · Mus musculus
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As of 2026-09-13Protein identity stays anchored to UniProt P23204. Use UniProt P23204 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P23204 as the stable identity anchor, then attach disease evidence before program review.
Peroxisome proliferator-activated receptor alpha
Review this target as Peroxisome proliferator-activated receptor alpha, mapped to UniProt P23204. Sequence length is 468 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Peroxisome proliferator-activated receptor alpha as ChEMBL target CHEMBL2128, mapped to UniProt P23204. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Peroxisome proliferator-activated receptor alpha |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P23204 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Peroxisome proliferator-activated receptor alpha |
| UniProt Accession | P23204 |
| Component Type | Protein |
| Sequence Length | 468 aa |
Peroxisome proliferator-activated receptor alpha
Review this target as Peroxisome proliferator-activated receptor alpha, mapped to UniProt P23204. Sequence length is 468 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL189116 | 9.82 | EC50 | 0.15 | Preclinical |
| CHEMBL191275 | 9.7 | EC50 | 0.2 | Preclinical |
| CHEMBL192518 | 9.57 | EC50 | 0.27 | Preclinical |
| CHEMBL191060 | 9.46 | EC50 | 0.35 | Preclinical |
| CHEMBL21241 | 9.0 | EC50 | 1.0 | Preclinical |
| CHEMBL364748 | 8.89 | EC50 | 1.3 | Preclinical |
| CHEMBL253310 | 8.7 | EC50 | 2.0 | Preclinical |
| CHEMBL4861761 | 8.52 | EC50 | 3.0 | Preclinical |
| CHEMBL4866115 | 8.52 | EC50 | 3.0 | Preclinical |
| CHEMBL278590 | 8.3 | EC50 | 5.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 37 | 57 | 5.8 |
| single protein format | 17 | 27 | 6.7 |
| assay format | 6 | 3 | 5.9 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 23 | 40 | 6.5 |
| assay format | 15 | 19 | 6.1 |
| organism-based format | 15 | 0 | — |