Use UniProt P35639 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL2146304 Target Snapshot
DNA damage-inducible transcript 3 protein · SINGLE PROTEIN · Mus musculus
Research home keeps recent targets
This target will appear in recent viewed items on this browser. Use the demo workspace to preview watch rules and decision queues.
Switch target
Move to another high-traffic target or paste a specific ChEMBL target ID.
Frame the target before identity details
Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt P35639. Use UniProt P35639 as the stable identity anchor, then attach disease evidence before program review.
DNA damage-inducible transcript 3 protein
Review this target as DNA damage-inducible transcript 3 protein, mapped to UniProt P35639. Sequence length is 168 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats DNA damage-inducible transcript 3 protein as ChEMBL target CHEMBL2146304, mapped to UniProt P35639. Disease framing currently uses the Open Targets-ready proxy contract.
Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.
Start with the right source
Choose the first block or source based on the question you are trying to answer.
Start here when your first question is whether DNA damage-inducible transcript 3 protein is the right protein anchor across sources, using UniProt P35639 as the stable mapping.
Jump to Protein ContextUse this block first when you need the strongest disease program and evidence level in one place.
Jump to Disease ContextOpen the one-page evidence card when you want the rationale, activity base, and attribution together.
Open Review-ready CardBasic Information
Verify identity, organism, and the fastest next research jumps from the same page.
| Preferred Name | DNA damage-inducible transcript 3 protein |
| Target Type | SINGLE PROTEIN |
| Organism | Mus musculus |
| UniProt | P35639 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | DNA damage-inducible transcript 3 protein |
| UniProt Accession | P35639 |
| Component Type | Protein |
| Sequence Length | 168 aa |
DNA damage-inducible transcript 3 protein
How to read this target
Review this target as DNA damage-inducible transcript 3 protein, mapped to UniProt P35639. Sequence length is 168 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1256686 | 6.8 | IC50 | 160.0 | Clinical |
| CHEMBL1387790 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1409900 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1411912 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1424264 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1429929 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1430895 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1459578 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1507250 | 6.8 | IC50 | 160.0 | Preclinical |
| CHEMBL1524484 | 6.8 | IC50 | 160.0 | Preclinical |
pChEMBL Value Distribution
Assay Landscape
Functional — 2 assays, 556 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 556 | 5.3 |
Binding — 2 assays, 0 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |
| cell-based format | 1 | 0 | — |