Nuclear receptor subfamily 1 group I member 2 · SINGLE PROTEIN · Rattus norvegicus
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As of 2026-09-14Protein identity stays anchored to UniProt Q9R1A7. Use UniProt Q9R1A7 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9R1A7 as the stable identity anchor, then attach disease evidence before program review.
Nuclear receptor subfamily 1 group I member 2
Review this target as Nuclear receptor subfamily 1 group I member 2, mapped to UniProt Q9R1A7. Sequence length is 431 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Nuclear receptor subfamily 1 group I member 2 as ChEMBL target CHEMBL2146315, mapped to UniProt Q9R1A7. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Nuclear receptor subfamily 1 group I member 2 |
| Target Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
| UniProt | Q9R1A7 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Nuclear receptor subfamily 1 group I member 2 |
| UniProt Accession | Q9R1A7 |
| Component Type | Protein |
| Sequence Length | 431 aa |
Nuclear receptor subfamily 1 group I member 2
Review this target as Nuclear receptor subfamily 1 group I member 2, mapped to UniProt Q9R1A7. Sequence length is 431 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL94657 | 8.0 | EC50 | 10.0 | Clinical |
| CHEMBL312862 | 7.05 | EC50 | 90.0 | Clinical |
| CHEMBL1237054 | 6.5 | EC50 | 320.0 | Approved |
| CHEMBL1200600 | 6.4 | EC50 | 400.0 | Approved |
| CHEMBL542541 | 6.35 | EC50 | 450.0 | Approved |
| CHEMBL1200617 | 6.17 | EC50 | 680.0 | Approved |
| CHEMBL1891684 | 5.75 | EC50 | 1800.0 | Clinical |
| CHEMBL98 | 5.6 | EC50 | 2500.0 | Approved |
| CHEMBL384467 | 5.58 | EC50 | 2600.0 | Approved |
| CHEMBL474260 | 5.55 | EC50 | 2800.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 14 | 34 | 5.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 5 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 0 | — |