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Target Snapshot

CHEMBL2163170 Target Snapshot

UDP-3-O-acyl-N-acetylglucosamine deacetylase · SINGLE PROTEIN · Pseudomonas aeruginosa

32Compounds
2Assays
0Approved Drugs
32.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt B5ATN6. Use UniProt B5ATN6 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt B5ATN6 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats UDP-3-O-acyl-N-acetylglucosamine deacetylase as ChEMBL target CHEMBL2163170, mapped to UniProt B5ATN6. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
UDP-3-O-acyl-N-acetylglucosamine deacetylase
SINGLE PROTEIN · Pseudomonas aeruginosa
As of 2026-09-14
ChEMBL target ID
CHEMBL2163170
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
B5ATN6
UDP-3-O-acyl-N-acetylglucosamine deacetylase
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether UDP-3-O-acyl-N-acetylglucosamine deacetylase is the right protein anchor across sources, using UniProt B5ATN6 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

Verify identity, organism, and the fastest next research jumps from the same page.

UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelUDP-3-O-acyl-N-acetylglucosamine deacetylase
UniProt AccessionB5ATN6
Component TypeProtein
Sequence Length197 aa

UDP-3-O-acyl-N-acetylglucosamine deacetylase

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as UDP-3-O-acyl-N-acetylglucosamine deacetylase, mapped to UniProt B5ATN6. Sequence length is 197 aa.

Mapped IDB5ATN6
Review nameUDP-3-O-acyl-N-acetylglucosamine deacetylase
OrganismPseudomonas aeruginosa
Clinical Profile

Clinical Phase Distribution

1
Phase I
Assay Mix

Activity Type Distribution

IC5032.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL2164511 9.29 IC50 0.511 Preclinical
CHEMBL4215934 9.21 IC50 0.62 Preclinical
CHEMBL2164521 9.18 IC50 0.657 Preclinical
CHEMBL3939284 9.17 IC50 0.68 Preclinical
CHEMBL5396682 9.15 IC50 0.71 Preclinical
CHEMBL2164512 9.07 IC50 0.85 Preclinical
CHEMBL2164522 9.04 IC50 0.912 Preclinical
CHEMBL2164523 8.92 IC50 1.2 Preclinical
CHEMBL2164524 8.86 IC50 1.39 Preclinical
CHEMBL2164513 8.79 IC50 1.61 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
3
7.5
7
8.0
11
8.5
7
9.0
0
9.5
pChEMBL
Assay Landscape

Assay Landscape

2
Total Assays
28
Tested Compounds
1
Assay Types
Binding — 2 assays, 28 compounds
BAO Format Assays Compounds Avg pChEMBL
assay format 1 5 8.6
single protein format 1 23 8.6

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine