Cdc2-related kinase · SINGLE PROTEIN · Leishmania major
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As of 2026-09-14Protein identity stays anchored to UniProt O96526. Use UniProt O96526 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt O96526 as the stable identity anchor, then attach disease evidence before program review.
cyclin-dependent kinase
Review this target as Cdc2-related kinase, mapped to UniProt O96526. ChEMBL maps the protein component as cyclin-dependent kinase. Sequence length is 311 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cdc2-related kinase as ChEMBL target CHEMBL2169723, mapped to UniProt O96526. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cdc2-related kinase |
| Target Type | SINGLE PROTEIN |
| Organism | Leishmania major |
| UniProt | O96526 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | cyclin-dependent kinase |
| UniProt Accession | O96526 |
| Component Type | Protein |
| Sequence Length | 311 aa |
cyclin-dependent kinase
Review this target as Cdc2-related kinase, mapped to UniProt O96526. ChEMBL maps the protein component as cyclin-dependent kinase. Sequence length is 311 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2171517 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL2171516 | 7.7 | IC50 | 20.0 | Preclinical |
| CHEMBL2171518 | 7.22 | IC50 | 60.0 | Preclinical |
| CHEMBL2171514 | 6.62 | IC50 | 240.0 | Preclinical |
| CHEMBL2171513 | 6.58 | IC50 | 260.0 | Preclinical |
| CHEMBL2171515 | 6.29 | IC50 | 510.0 | Preclinical |
| CHEMBL1401272 | 5.82 | IC50 | 1500.0 | Preclinical |
| CHEMBL2171512 | 5.28 | IC50 | 5300.0 | Preclinical |
| CHEMBL1328065 | 4.96 | IC50 | 11000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 9 | 6.5 |